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徐健

姓  名:

徐健

性  别:

学科类别:

分析化学

单位代码:

121B62

学  历:

博士

职  称:

副研究员 

电  话:

0931-4968250

传  真:

0931-4968019 

职  务:

 

电子邮件:

xujian1980@licp.cas.cn

通讯地址:

中国甘肃省兰州市天水中路18号中国科学院兰州化学物理研究所环境材料与生态化学研究发展中心,730000

简  历:

    徐健,博士,甘肃天水人,中国科学院兰州化学物理研究所副研究员。20026月在兰州大学生物系获生物化学学士学位,20146月在中国科学院兰州化学物理研究所获分析化学博士学位。20027月至20207月供职于中国科学院兰州化学物理研究所,任助理研究员。2016年入选中国科学院西部之光人才培养对象,201812月至201912月,新加坡国立大学访问学者,20208月晋升为副研究员。

代表性成果:

主持项目

[1] 国家自然科学基金青年科学基金项目,针对醌氧化还原酶的荧光探针设计与活体癌细胞成像研究。

[2] 中国科学院西部之光青年学者B类项目,中药天然药物分离材料研究。

[3] 甘肃省青年科技基金计划项目,以组蛋白去乙酰化酶为靶标的近红外荧光分子探针研究。

[4] 中国科学院重点实验室开放课题,有机功能化介孔材料制备与天然药物活性成分分离新技术研究。

[5] 横向项目,长宏公司马铃薯淀粉加工废水还田利用实施方案。

 

学术论文 

[1] Xiqiong Mu, Yinquan Wang, Bo Qian, Gang Liu, Jian Xu*, Fankui Zeng*, Monitoring of organophosphorus pesticide residues in plant and vegetable tissues by a novel silver nanocluster probe, Analytical Methods, 2023, 15, 762-770;

[2] Quanzhi Yang, Yujie Wen, Jian Xu*, Shijun Shao*, An HBT-based fluorescent dye with enhanced quantum yield in water system and its application for constructing NQO1 fluorescent probe, Talanta, 2020, 216, 120982-120988;

[3] Litao Wang, Jiasheng Wang, Jian Xu*, Sheng Liu, Suzhen Huang, Siqi Han, Yunyu Liu, Mei Lv*, Highly sensitive qualitative and quantitative detection of saturated fatty aldehydes in edible vegetable oils using a “turn-on” fluorescent probe by high performance liquid chromatography, Journal of Chromatography A, 2020, 1621,461063-461069;

[4] Yue Ni, Hong Liu, Di Dai, Xiqiong Mu, Jian Xu*, Shijun Shao*, Chromogenic, fluorescent and redox sensors for multichannel imaging and detection of hydrogen peroxide in living cell systems, Analytical Chemistry, 2018, 90, 10152-10158;

[5] Hui Yu, Yongna Wu, Yue Hu, Xudong Gao, Qing Liang, Jian Xu*, Shijun Shao*, Dual-functional fluorescent probe responds to hypochlorous acid and SO2 derivatives with different fluorescence signals, Talanta, 2017, 165, 625-631;

[6] Hui Yu, Yan Liu, Jiamin Wang, Qing Liang, Hong Liu, Jian Xu*, Shijun Shao*, A gold nanocluster-based ratiometric fluorescent probe for cysteine and homocysteine detection in living cells, New J. Chem., 2017, 41, 4416-4423;

[7] Jian Xu, Yan Zhang, Hui Yu, Xudong Gao, Shijun Shao*, Mitochondria-targeted fluorescent probe for imaging hydrogen peroxide in living cells, Analytical Chemistry, 2016, 88,1455-1461;

[8] Jian Xu, Hui Yu, Yue Hu, Mingzhong Chen, Shijun Shao*, A gold nanoparticle-based fluorescence sensor for high sensitive and selective detection of thiols in living cells, Biosensors and Bioelectronics, 2016, 75, 1-7;

[9] Jian Xu, Shaobo Sun, Qian Li, Ying Yue, Yingdong Li, Shijun Shao*, A rapid response ‘‘Turn-On’’ fluorescent probe for nitroreductase detection and its application in hypoxic tumor cell imaging, Analyst, 2015, 140, 574-581;

[10] Jian Xu, Qian Li, Ying Yue, Yong Guo, Shijun Shao*, A water-soluble BODIPY derivative as a highly selective ‘‘Turn-On’’ fluorescent sensor for H2O2 sensing in vivo, Biosensors and Bioelectronics, 2014, 56, 58-63;

[11] Jian Xu, Shaobo Sun, Qian Li, Ying Yue, Yingdong Li, Shijun Shao*, A novel ''Turn-On'' fluorescent probe for F- detection in aqueous solution and its application in live-cell imaging, Analytica Chimica Acta, 2014, 849, 36-42;

[12] Jian Xu, Kai Liu, Duolong Di, Shijun Shao, Yong Guo*, A selective colorimetric chemosensor for detecting SO32- in neutral aqueous solution, Inorganic Chemistry Communications, 2007, 10, 681-684.

 

专利 

[1] 徐健,曾凡逵,穆希琼,刘刚, 一种快速检测草甘膦农药的银纳米簇探针及其应用, 202211195775.X.

[2] 徐健,邵士俊,梁卿,刘红,一种具有线粒体靶向功能的过氧化氢荧光探针及应用, 201610322293.4.

[3] 刘红,岳莹,邵士俊,梁卿, 徐健,一种从玉米蛋白粉中连续提取玉米黄色素与玉米醇溶蛋白的方法, ZL201610358357.6.

[4] 刘红,邵士俊,徐健,梁卿, 一种白色玉米醇溶蛋白的中试生产线, ZL201621322594.9.

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